Home The Active Ingredient Matrix 2'-Fucosyllactose

Formulation Intelligence

2'-Fucosyllactose

Accelerate your CDMO or DTC pipeline. Map the exact physiochemical constraints, bioavailability synergies, and optimal delivery mechanisms for 2'-Fucosyllactose.

A human milk oligosaccharide (HMO) that functions as a prebiotic and decoy receptor to modulate gut microbiota composition and inhibit pathogen adhesion to the intestinal epithelium.

Verified Molecular Profiling (NIH PubChem)

PubChem CID

119538

Molecular Weight

913.0 g/mol

XLogP3 (Lipophilicity)

-3.9

IUPAC Name

12-[2,3-dihydroxy-2-(hydroxymethyl)propyl]-22,23-dihydroxy-6-(1-hydroxyethyl)-3-(hydroxymethyl)-18-methyl-15-[(2-methylsulfonyl-1H-indol-3-yl)methyl]-9-propan-2-yl-1,4,7,10,13,16,19-heptazabicyclo[19.3.0]tetracosane-2,5,8,11,14,17,20-heptone

Pharmacokinetic Synergies & Enhancers

Proven Synergy Pairings

  • Bifidobacterium infantis for selective proliferation and metabolic cross-feeding
  • Lactoferrin for synergistic antimicrobial activity and immune system maturation

Biological Formulation Enhancers

  • Galactooligosaccharides (GOS) for broadening the prebiotic spectrum and enhancing bifidogenic response
  • Vitamin D3 for potentiating intestinal barrier function and mucosal immunity

Delivery System Constraints & Modeling

Every active compound behaves uniquely based on the physical matrix it is suspended in. Below are the known physical chemistry challenges for 2'-Fucosyllactose across standard consumer modalities.

💊 Standard Capsules

High hygroscopicity of 2'-FL requires moisture-resistant HPMC capsules and desiccants to prevent clumping or degradation.

🍬 Gummy & Pectin Formats

The high inclusion levels required for clinical efficacy can interfere with pectin gelation and result in a sticky, unstable texture.

🔬 Thin-Film Oral Strips

Significant dosage requirements typically exceeding 200mg per serving surpass the limited payload capacity of standard thin-film polymer matrices.

For Brand Founders

Formulate with 2'-Fucosyllactose

Ready to launch a product featuring 2'-Fucosyllactose? Skip months of expensive wet-lab iterations. Generate a manufacturer-ready formulation in hours, instantly screened for physical incompatibilities and global regulatory compliance.

Build Science-Backed Formulation

Efficacy Evidence

Maximize 2'-Fucosyllactose Bioavailability

Need absolute proof that your 2'-Fucosyllactose extract actually absorbs? Stop blindly combining generic powders. Run a physics-based PBPK simulation to mathematically engineer peak clinical efficacy and targeted plasma concentrations.

Simulate Bioavailability

For R&D Labs & CDMOs

2'-Fucosyllactose Degradation Testing

Is your 2'-Fucosyllactose payload degrading in the capsule before the expiration date? Stop waiting for costly bench testing. Run an accelerated digital twin to precisely model oxidation pathways and pH shifts before finalizing a manufacturing run.

Model Active Degradation