Home The Active Ingredient Matrix Boswellia serrata (3-O-acetyl-11-keto-beta-boswellic acid)

Formulation Intelligence

Boswellia serrata (3-O-acetyl-11-keto-beta-boswellic acid)

Accelerate your CDMO or DTC pipeline. Map the exact physiochemical constraints, bioavailability synergies, and optimal delivery mechanisms for Boswellia serrata (3-O-acetyl-11-keto-beta-boswellic acid).

A potent pentacyclic triterpenoid extract that selectively inhibits 5-lipoxygenase (5-LOX) to modulate leukotriene synthesis for the management of chronic inflammatory conditions like osteoarthritis and asthma.

Verified Molecular Profiling (NIH PubChem)

PubChem CID

11386456

Molecular Weight

498.7 g/mol

XLogP3 (Lipophilicity)

7.7

IUPAC Name

methyl (1R,2R,5S,8R,9R,10R,13R,14R,20R)-1,2,14,19,19-pentamethyl-16,18-dioxo-8-prop-1-en-2-yl-17-oxapentacyclo[11.9.0.02,10.05,9.014,20]docosane-5-carboxylate

Pharmacokinetic Synergies & Enhancers

Proven Synergy Pairings

  • Curcumin for synergistic inhibition of NF-kB and 5-LOX pathways
  • Glucosamine for structural joint support alongside anti-inflammatory action

Biological Formulation Enhancers

  • Lecithin for phytosome formation to overcome poor lipophilic absorption
  • Piperine for inhibition of metabolic glucuronidation

Delivery System Constraints & Modeling

Every active compound behaves uniquely based on the physical matrix it is suspended in. Below are the known physical chemistry challenges for Boswellia serrata (3-O-acetyl-11-keto-beta-boswellic acid) across standard consumer modalities.

💊 Standard Capsules

The resinous nature of the extract requires high-quality flow agents like silicon dioxide to prevent clumping and ensure uniform filling during high-speed encapsulation.

🍬 Gummy & Pectin Formats

The high lipid content and distinct resinous odor pose significant challenges for flavor masking and can interfere with the pectin gelling matrix stability.

🔬 Thin-Film Oral Strips

The high therapeutic dose required (typically >100mg) exceeds the standard 50mg payload capacity of thin-film polymer matrices.

For Brand Founders

Formulate with Boswellia serrata (3-O-acetyl-11-keto-beta-boswellic acid)

Ready to launch a product featuring Boswellia serrata (3-O-acetyl-11-keto-beta-boswellic acid)? Skip months of expensive wet-lab iterations. Generate a manufacturer-ready formulation in hours, instantly screened for physical incompatibilities and global regulatory compliance.

Build Science-Backed Formulation

Efficacy Evidence

Maximize Boswellia serrata (3-O-acetyl-11-keto-beta-boswellic acid) Bioavailability

Need absolute proof that your Boswellia serrata (3-O-acetyl-11-keto-beta-boswellic acid) extract actually absorbs? Stop blindly combining generic powders. Run a physics-based PBPK simulation to mathematically engineer peak clinical efficacy and targeted plasma concentrations.

Simulate Bioavailability

For R&D Labs & CDMOs

Boswellia serrata (3-O-acetyl-11-keto-beta-boswellic acid) Degradation Testing

Is your Boswellia serrata (3-O-acetyl-11-keto-beta-boswellic acid) payload degrading in the capsule before the expiration date? Stop waiting for costly bench testing. Run an accelerated digital twin to precisely model oxidation pathways and pH shifts before finalizing a manufacturing run.

Model Active Degradation