Home The Active Ingredient Matrix Dandelion Root (Taraxasterol)

Formulation Intelligence

Dandelion Root (Taraxasterol)

Accelerate your CDMO or DTC pipeline. Map the exact physiochemical constraints, bioavailability synergies, and optimal delivery mechanisms for Dandelion Root (Taraxasterol).

Dandelion root extract functions as a potassium-sparing diuretic and cholagogue, modulating hepatic detoxification pathways and renal fluid excretion through sesquiterpene lactones and triterpenoid activity.

Verified Molecular Profiling (NIH PubChem)

PubChem CID

92103

Molecular Weight

740.7 g/mol

XLogP3 (Lipophilicity)

-3.4

IUPAC Name

4-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-3-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-5-one

Pharmacokinetic Synergies & Enhancers

Proven Synergy Pairings

  • Milk Thistle for enhanced hepatoprotective synergy and bile flow stimulation
  • Potassium for offsetting potential electrolyte imbalances despite its potassium-sparing nature

Biological Formulation Enhancers

  • Piperine for increasing the bioavailability of triterpenoid compounds via CYP3A4 inhibition
  • Lecithin for improving the micellar solubilization of lipophilic sesquiterpene lactones

Delivery System Constraints & Modeling

Every active compound behaves uniquely based on the physical matrix it is suspended in. Below are the known physical chemistry challenges for Dandelion Root (Taraxasterol) across standard consumer modalities.

💊 Standard Capsules

The hygroscopic nature of the 4:1 concentrated extract requires moisture-resistant excipients to prevent clumping and degradation within the gelatin or HPMC shell.

🍬 Gummy & Pectin Formats

High concentrations of dandelion extract introduce significant bitterness and an earthy flavor profile that is difficult to mask without compromising the pectin matrix integrity or sugar content.

🔬 Thin-Film Oral Strips

The high dosage required for a 4:1 extract exceeds the typical 50mg payload capacity of thin-film polymers, leading to structural brittleness.

For Brand Founders

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Efficacy Evidence

Maximize Dandelion Root (Taraxasterol) Bioavailability

Need absolute proof that your Dandelion Root (Taraxasterol) extract actually absorbs? Stop blindly combining generic powders. Run a physics-based PBPK simulation to mathematically engineer peak clinical efficacy and targeted plasma concentrations.

Simulate Bioavailability

For R&D Labs & CDMOs

Dandelion Root (Taraxasterol) Degradation Testing

Is your Dandelion Root (Taraxasterol) payload degrading in the capsule before the expiration date? Stop waiting for costly bench testing. Run an accelerated digital twin to precisely model oxidation pathways and pH shifts before finalizing a manufacturing run.

Model Active Degradation