Home The Active Ingredient Matrix Blackcurrant Extract (Delphinidin-3-rutinoside)

Formulation Intelligence

Blackcurrant Extract (Delphinidin-3-rutinoside)

Accelerate your CDMO or DTC pipeline. Map the exact physiochemical constraints, bioavailability synergies, and optimal delivery mechanisms for Blackcurrant Extract (Delphinidin-3-rutinoside).

Delphinidin-3-rutinoside is a potent anthocyanin glycoside that modulates rhodopsin regeneration and inhibits vascular endothelial growth factor (VEGF) expression to support ocular microcirculation and retinal health.

Verified Molecular Profiling (NIH PubChem)

PubChem CID

44256722

Molecular Weight

611.5 g/mol

XLogP3 (Lipophilicity)

N/A

IUPAC Name

(2R,5S)-2-[[(3R,6S)-6-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromenylium-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol

Pharmacokinetic Synergies & Enhancers

Proven Synergy Pairings

  • Lutein for synergistic protection against blue-light induced oxidative stress in retinal pigment epithelial cells
  • Vitamin C for the regeneration of the anthocyanidin cation and enhanced antioxidant stability

Biological Formulation Enhancers

  • Phosphatidylcholine for the formation of phytosomes to overcome the low lipophilicity and poor intestinal permeability of polar glycosides
  • Quercetin for the inhibition of glucuronidation and sulfation pathways to extend the plasma half-life of the molecule

Delivery System Constraints & Modeling

Every active compound behaves uniquely based on the physical matrix it is suspended in. Below are the known physical chemistry challenges for Blackcurrant Extract (Delphinidin-3-rutinoside) across standard consumer modalities.

💊 Standard Capsules

The high hygroscopicity of anthocyanin extracts requires moisture-barrier HPMC capsules and desiccants to prevent oxidative degradation and clumping.

🍬 Gummy & Pectin Formats

Maintaining a low pH environment (below 3.5) is critical to preserve the flavylium cation's stability and prevent undesirable color shifts from deep purple to colorless or brown.

🔬 Thin-Film Oral Strips

The high therapeutic dose required for clinical efficacy often exceeds the 20-50mg payload capacity of standard polymer matrices, limiting the strip to a supplemental rather than primary delivery format.

For Brand Founders

Formulate with Blackcurrant Extract (Delphinidin-3-rutinoside)

Ready to launch a product featuring Blackcurrant Extract (Delphinidin-3-rutinoside)? Skip months of expensive wet-lab iterations. Generate a manufacturer-ready formulation in hours, instantly screened for physical incompatibilities and global regulatory compliance.

Build Science-Backed Formulation

Efficacy Evidence

Maximize Blackcurrant Extract (Delphinidin-3-rutinoside) Bioavailability

Need absolute proof that your Blackcurrant Extract (Delphinidin-3-rutinoside) extract actually absorbs? Stop blindly combining generic powders. Run a physics-based PBPK simulation to mathematically engineer peak clinical efficacy and targeted plasma concentrations.

Simulate Bioavailability

For R&D Labs & CDMOs

Blackcurrant Extract (Delphinidin-3-rutinoside) Degradation Testing

Is your Blackcurrant Extract (Delphinidin-3-rutinoside) payload degrading in the capsule before the expiration date? Stop waiting for costly bench testing. Run an accelerated digital twin to precisely model oxidation pathways and pH shifts before finalizing a manufacturing run.

Model Active Degradation