Home The Active Ingredient Matrix Echinacea purpurea (Cichoric acid)

Formulation Intelligence

Echinacea purpurea (Cichoric acid)

Accelerate your CDMO or DTC pipeline. Map the exact physiochemical constraints, bioavailability synergies, and optimal delivery mechanisms for Echinacea purpurea (Cichoric acid).

Cichoric acid acts as a potent immunomodulator and hyaluronidase inhibitor, enhancing phagocytosis and stimulating the proliferation of T-lymphocytes to bolster innate and adaptive immune responses.

Verified Molecular Profiling (NIH PubChem)

PubChem CID

5281764

Molecular Weight

474.4 g/mol

XLogP3 (Lipophilicity)

2

IUPAC Name

(2R,3R)-2,3-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]butanedioic acid

Pharmacokinetic Synergies & Enhancers

Proven Synergy Pairings

  • Elderberry (Sambucus nigra) for synergistic antiviral inhibition of hemagglutinin and neuraminidase proteins
  • Zinc for enhanced T-cell maturation and stabilization of the immune response during acute viral challenge

Biological Formulation Enhancers

  • Phosphatidylcholine for the formation of phytosomes to overcome the low lipophilicity and poor intestinal permeability of phenolic acids
  • Ascorbyl palmitate for protecting the highly labile cichoric acid from oxidative degradation during storage and gastric transit

Delivery System Constraints & Modeling

Every active compound behaves uniquely based on the physical matrix it is suspended in. Below are the known physical chemistry challenges for Echinacea purpurea (Cichoric acid) across standard consumer modalities.

💊 Standard Capsules

The hygroscopic nature of Echinacea extracts requires moisture-resistant HPMC capsules to prevent clumping and degradation of the phenolic content.

🍬 Gummy & Pectin Formats

The high acidity and phenolic profile of cichoric acid can interfere with pectin gelation kinetics, potentially leading to a soft or unstable matrix.

🔬 Thin-Film Oral Strips

The significant dosage required for therapeutic efficacy exceeds the standard 20-40mg payload capacity of thin-film polymer matrices.

For Brand Founders

Formulate with Echinacea purpurea (Cichoric acid)

Ready to launch a product featuring Echinacea purpurea (Cichoric acid)? Skip months of expensive wet-lab iterations. Generate a manufacturer-ready formulation in hours, instantly screened for physical incompatibilities and global regulatory compliance.

Build Science-Backed Formulation

Efficacy Evidence

Maximize Echinacea purpurea (Cichoric acid) Bioavailability

Need absolute proof that your Echinacea purpurea (Cichoric acid) extract actually absorbs? Stop blindly combining generic powders. Run a physics-based PBPK simulation to mathematically engineer peak clinical efficacy and targeted plasma concentrations.

Simulate Bioavailability

For R&D Labs & CDMOs

Echinacea purpurea (Cichoric acid) Degradation Testing

Is your Echinacea purpurea (Cichoric acid) payload degrading in the capsule before the expiration date? Stop waiting for costly bench testing. Run an accelerated digital twin to precisely model oxidation pathways and pH shifts before finalizing a manufacturing run.

Model Active Degradation