Home The Active Ingredient Matrix Ellagic Acid

Formulation Intelligence

Ellagic Acid

Accelerate your CDMO or DTC pipeline. Map the exact physiochemical constraints, bioavailability synergies, and optimal delivery mechanisms for Ellagic Acid.

Ellagic acid is a polyphenolic antioxidant that exerts potent chemopreventive and anti-inflammatory effects by modulating the NF-κB pathway and inhibiting oxidative stress-induced DNA damage.

Verified Molecular Profiling (NIH PubChem)

PubChem CID

5281855

Molecular Weight

302.19 g/mol

XLogP3 (Lipophilicity)

1.1

IUPAC Name

6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.04,16.011,15]hexadeca-1(15),4,6,8(16),11,13-hexaene-3,10-dione

Pharmacokinetic Synergies & Enhancers

Proven Synergy Pairings

  • Quercetin for enhanced antioxidant capacity and cellular protection
  • Resveratrol for synergistic inhibition of pro-inflammatory cytokines

Biological Formulation Enhancers

  • Piperine for inhibition of glucuronidation to increase systemic bioavailability
  • Phosphatidylcholine for the creation of phytosomes to improve intestinal permeability

Delivery System Constraints & Modeling

Every active compound behaves uniquely based on the physical matrix it is suspended in. Below are the known physical chemistry challenges for Ellagic Acid across standard consumer modalities.

💊 Standard Capsules

Ellagic acid exhibits poor aqueous solubility and low bioavailability, requiring micronization or complexation to ensure consistent absorption in dry powder formats.

🍬 Gummy & Pectin Formats

The high polyphenolic content can cause significant astringency and potential cross-linking with pectin matrices, which may negatively impact the final texture and flavor profile.

🔬 Thin-Film Oral Strips

The relatively high therapeutic dose required for ellagic acid typically exceeds the 20-30mg payload capacity of thin-film oral strips, limiting its application in this format.

For Brand Founders

Formulate with Ellagic Acid

Ready to launch a product featuring Ellagic Acid? Skip months of expensive wet-lab iterations. Generate a manufacturer-ready formulation in hours, instantly screened for physical incompatibilities and global regulatory compliance.

Build Science-Backed Formulation

Efficacy Evidence

Maximize Ellagic Acid Bioavailability

Need absolute proof that your Ellagic Acid extract actually absorbs? Stop blindly combining generic powders. Run a physics-based PBPK simulation to mathematically engineer peak clinical efficacy and targeted plasma concentrations.

Simulate Bioavailability

For R&D Labs & CDMOs

Ellagic Acid Degradation Testing

Is your Ellagic Acid payload degrading in the capsule before the expiration date? Stop waiting for costly bench testing. Run an accelerated digital twin to precisely model oxidation pathways and pH shifts before finalizing a manufacturing run.

Model Active Degradation