Hericium erinaceus (Erinacine A)

Accelerate your CDMO or DTC pipeline. Map the exact physiochemical constraints, bioavailability synergies, and optimal delivery mechanisms for Hericium erinaceus (Erinacine A).

Erinacine A functions as a potent low-molecular-weight stimulator of Nerve Growth Factor (NGF) synthesis through the activation of the JNK signaling pathway, facilitating neurogenesis and myelin sheath repair.

Verified Molecular Profiling (NIH PubChem)

PubChem CID

10141644

Molecular Weight

498.4 g/mol

XLogP3 (Lipophilicity)

N/A

IUPAC Name

[(1R)-3-methyl-1-[[(2S)-2-(morpholine-4-carbonylamino)-3-[4-(pyridin-2-ylmethoxy)phenyl]propanoyl]amino]butyl]boronic acid

Pharmacokinetic Synergies & Enhancers

Proven Synergy Pairings

Hericenones for complementary peripheral NGF induction
Bacopa monnieri for synergistic upregulation of BDNF signaling

Biological Formulation Enhancers

Lecithin for enhanced lipophilic transport across the blood-brain barrier
Piperine for inhibition of first-pass metabolic degradation

Delivery System Constraints & Modeling

Every active compound behaves uniquely based on the physical matrix it is suspended in. Below are the known physical chemistry challenges for Hericium erinaceus (Erinacine A) across standard consumer modalities.

💊 Standard Capsules

The high hygroscopicity of concentrated Hericium extracts requires moisture-resistant HPMC shells and desiccants to prevent clumping and oxidative degradation.

🍬 Gummy & Pectin Formats

Thermal degradation of erinacines during the high-heat pectin setting process necessitates precise temperature control or post-cooling infusion to maintain bioactivity.

🔬 Thin-Film Oral Strips

The high effective dose required for neurotrophic support typically exceeds the 50mg payload capacity of standard thin-film polymer matrices, limiting formulation feasibility.

For Brand Founders

Formulate with Hericium erinaceus (Erinacine A)

Ready to launch a product featuring Hericium erinaceus (Erinacine A)? Skip months of expensive wet-lab iterations. Generate a manufacturer-ready formulation in hours, instantly screened for physical incompatibilities and global regulatory compliance.

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Efficacy Evidence

Maximize Hericium erinaceus (Erinacine A) Bioavailability

Need absolute proof that your Hericium erinaceus (Erinacine A) extract actually absorbs? Stop blindly combining generic powders. Run a physics-based PBPK simulation to mathematically engineer peak clinical efficacy and targeted plasma concentrations.

Simulate Bioavailability

For R&D Labs & CDMOs

Hericium erinaceus (Erinacine A) Degradation Testing

Is your Hericium erinaceus (Erinacine A) payload degrading in the capsule before the expiration date? Stop waiting for costly bench testing. Run an accelerated digital twin to precisely model oxidation pathways and pH shifts before finalizing a manufacturing run.

Model Active Degradation