Inonotus obliquus (Betulinic acid)

Accelerate your CDMO or DTC pipeline. Map the exact physiochemical constraints, bioavailability synergies, and optimal delivery mechanisms for Inonotus obliquus (Betulinic acid).

Inonotus obliquus functions as a potent immunomodulator and antineoplastic agent by leveraging betulinic acid to induce mitochondrial-mediated apoptosis in malignant cells while suppressing NF-κB-driven inflammatory cascades.

Verified Molecular Profiling (NIH PubChem)

PubChem CID

64971

Molecular Weight

456.7 g/mol

XLogP3 (Lipophilicity)

8.2

IUPAC Name

(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid

Pharmacokinetic Synergies & Enhancers

Proven Synergy Pairings

Vitamin C for enhanced collagen synthesis and potentiation of antioxidant defense systems
Quercetin for synergistic inhibition of pro-inflammatory cytokine production

Biological Formulation Enhancers

Piperine for inhibition of P-glycoprotein and CYP3A4 to increase systemic bioavailability
Hydroxypropyl-beta-cyclodextrin for enhancing the aqueous solubility of the hydrophobic triterpenoid fraction

Delivery System Constraints & Modeling

Every active compound behaves uniquely based on the physical matrix it is suspended in. Below are the known physical chemistry challenges for Inonotus obliquus (Betulinic acid) across standard consumer modalities.

💊 Standard Capsules

The hygroscopic nature of concentrated Chaga extracts requires moisture-resistant HPMC shells to prevent powder clumping and premature degradation.

🍬 Gummy & Pectin Formats

High concentrations of betulinic acid can impart a gritty mouthfeel and disrupt the pectin cross-linking matrix, leading to structural instability.

🔬 Thin-Film Oral Strips

The high molecular weight and hydrophobic profile of betulinic acid limit its loading capacity within the polymer matrix, often resulting in film brittleness and poor dissolution.

For Brand Founders

Formulate with Inonotus obliquus (Betulinic acid)

Ready to launch a product featuring Inonotus obliquus (Betulinic acid)? Skip months of expensive wet-lab iterations. Generate a manufacturer-ready formulation in hours, instantly screened for physical incompatibilities and global regulatory compliance.

Build Science-Backed Formulation

Efficacy Evidence

Maximize Inonotus obliquus (Betulinic acid) Bioavailability

Need absolute proof that your Inonotus obliquus (Betulinic acid) extract actually absorbs? Stop blindly combining generic powders. Run a physics-based PBPK simulation to mathematically engineer peak clinical efficacy and targeted plasma concentrations.

Simulate Bioavailability

For R&D Labs & CDMOs

Inonotus obliquus (Betulinic acid) Degradation Testing

Is your Inonotus obliquus (Betulinic acid) payload degrading in the capsule before the expiration date? Stop waiting for costly bench testing. Run an accelerated digital twin to precisely model oxidation pathways and pH shifts before finalizing a manufacturing run.

Model Active Degradation