Wild Lettuce (Lactucin)

Accelerate your CDMO or DTC pipeline. Map the exact physiochemical constraints, bioavailability synergies, and optimal delivery mechanisms for Wild Lettuce (Lactucin).

Lactuca virosa functions primarily as a mild sedative and analgesic via the modulation of adenosine receptors and potential inhibition of enkephalinase, making it a candidate for non-opioid pain management and sleep induction.

Verified Molecular Profiling (NIH PubChem)

PubChem CID

119144

Molecular Weight

632.7 g/mol

XLogP3 (Lipophilicity)

N/A

IUPAC Name

(6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;bis(sodium hydride)

Pharmacokinetic Synergies & Enhancers

Proven Synergy Pairings

Valeriana officinalis for potentiating GABAergic sedative effects
Humulus lupulus for synergistic sleep-latency reduction via circadian rhythm modulation

Biological Formulation Enhancers

Piperine for increasing intestinal permeability and metabolic stability of sesquiterpene lactones
Quercetin for inhibiting P-glycoprotein-mediated efflux of bitter sesquiterpenes

Delivery System Constraints & Modeling

Every active compound behaves uniquely based on the physical matrix it is suspended in. Below are the known physical chemistry challenges for Wild Lettuce (Lactucin) across standard consumer modalities.

💊 Standard Capsules

The hygroscopic nature of concentrated lactucarium extracts requires moisture-barrier excipients to prevent clumping and degradation within the gelatin shell.

🍬 Gummy & Pectin Formats

The intense bitterness of sesquiterpene lactones necessitates high-potency masking agents and may interfere with pectin gelation at high concentrations.

🔬 Thin-Film Oral Strips

The low therapeutic threshold and high molecular weight of the crude extract limit the total payload capacity, often requiring micronized isolates for effective thin-film integration.

For Brand Founders

Formulate with Wild Lettuce (Lactucin)

Ready to launch a product featuring Wild Lettuce (Lactucin)? Skip months of expensive wet-lab iterations. Generate a manufacturer-ready formulation in hours, instantly screened for physical incompatibilities and global regulatory compliance.

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Efficacy Evidence

Maximize Wild Lettuce (Lactucin) Bioavailability

Need absolute proof that your Wild Lettuce (Lactucin) extract actually absorbs? Stop blindly combining generic powders. Run a physics-based PBPK simulation to mathematically engineer peak clinical efficacy and targeted plasma concentrations.

Simulate Bioavailability

For R&D Labs & CDMOs

Wild Lettuce (Lactucin) Degradation Testing

Is your Wild Lettuce (Lactucin) payload degrading in the capsule before the expiration date? Stop waiting for costly bench testing. Run an accelerated digital twin to precisely model oxidation pathways and pH shifts before finalizing a manufacturing run.

Model Active Degradation