Home The Active Ingredient Matrix Lycium barbarum (Zeaxanthin dipalmitate)

Formulation Intelligence

Lycium barbarum (Zeaxanthin dipalmitate)

Accelerate your CDMO or DTC pipeline. Map the exact physiochemical constraints, bioavailability synergies, and optimal delivery mechanisms for Lycium barbarum (Zeaxanthin dipalmitate).

Zeaxanthin dipalmitate acts as a highly lipophilic macular carotenoid ester that selectively accumulates in the fovea centralis to attenuate photo-oxidative damage and enhance visual acuity via blue-light filtration.

Verified Molecular Profiling (NIH PubChem)

PubChem CID

5281250

Molecular Weight

1045.7 g/mol

XLogP3 (Lipophilicity)

26.7

IUPAC Name

[(1R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-hexadecanoyloxy-2,6,6-trimethylcyclohexen-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethylcyclohex-3-en-1-yl] hexadecanoate

Pharmacokinetic Synergies & Enhancers

Proven Synergy Pairings

  • Lutein for competitive macular pigment density enhancement
  • Meso-zeaxanthin for comprehensive foveal coverage
  • Zinc for supporting retinol dehydrogenase activity

Biological Formulation Enhancers

  • Medium-chain triglycerides (MCTs) for micellar solubilization of lipophilic esters
  • Piperine for inhibition of CYP3A4-mediated first-pass metabolism

Delivery System Constraints & Modeling

Every active compound behaves uniquely based on the physical matrix it is suspended in. Below are the known physical chemistry challenges for Lycium barbarum (Zeaxanthin dipalmitate) across standard consumer modalities.

💊 Standard Capsules

The high susceptibility of carotenoid esters to photo-oxidation and thermal degradation necessitates the use of opaque capsule shells and nitrogen-purged filling environments.

🍬 Gummy & Pectin Formats

Incorporating hydrophobic zeaxanthin dipalmitate into a hydrophilic pectin matrix risks lipid migration and surface sweating, potentially compromising shelf-life stability.

🔬 Thin-Film Oral Strips

The significant molecular weight and required therapeutic dosage of zeaxanthin dipalmitate exceed the typical 20-40mg payload capacity of thin-film polymer matrices.

For Brand Founders

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Efficacy Evidence

Maximize Lycium barbarum (Zeaxanthin dipalmitate) Bioavailability

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For R&D Labs & CDMOs

Lycium barbarum (Zeaxanthin dipalmitate) Degradation Testing

Is your Lycium barbarum (Zeaxanthin dipalmitate) payload degrading in the capsule before the expiration date? Stop waiting for costly bench testing. Run an accelerated digital twin to precisely model oxidation pathways and pH shifts before finalizing a manufacturing run.

Model Active Degradation