Paeonia lactiflora (Paeoniflorin)

Accelerate your CDMO or DTC pipeline. Map the exact physiochemical constraints, bioavailability synergies, and optimal delivery mechanisms for Paeonia lactiflora (Paeoniflorin).

Paeoniflorin is a monoterpene glycoside that exerts immunomodulatory and neuroprotective effects by inhibiting the TLR4/NF-κB signaling pathway and modulating the hypothalamic-pituitary-adrenal axis.

Verified Molecular Profiling (NIH PubChem)

PubChem CID

442534

Molecular Weight

480.5 g/mol

XLogP3 (Lipophilicity)

-1

IUPAC Name

[(1R,2S,3R,5R,6R,8S)-6-hydroxy-8-methyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9,10-dioxatetracyclo[4.3.1.02,5.03,8]decan-2-yl]methyl benzoate

Pharmacokinetic Synergies & Enhancers

Proven Synergy Pairings

Glycyrrhizin for synergistic antispasmodic activity and enhanced anti-inflammatory response in smooth muscle tissues
Glucosamine for potentiated chondroprotective effects in autoimmune-mediated joint degradation

Biological Formulation Enhancers

Piperine for inhibition of P-glycoprotein-mediated efflux to enhance systemic absorption
Quercetin for synergistic suppression of pro-inflammatory cytokines and improved metabolic stability

Delivery System Constraints & Modeling

Every active compound behaves uniquely based on the physical matrix it is suspended in. Below are the known physical chemistry challenges for Paeonia lactiflora (Paeoniflorin) across standard consumer modalities.

💊 Standard Capsules

The hygroscopic nature of standardized Paeonia extracts necessitates the use of moisture-barrier excipients like magnesium stearate or silica to prevent powder caking and ensure dose uniformity.

🍬 Gummy & Pectin Formats

The inherent bitterness and astringency of paeoniflorin require complex flavor-masking agents and may destabilize pectin-based matrices if the extract's organic acid content is not neutralized.

🔬 Thin-Film Oral Strips

Limited surface area and polymer matrix capacity of thin films restrict the delivery of therapeutic dosages, as standardized extracts typically require high milligram payloads per serving.

For Brand Founders

Formulate with Paeonia lactiflora (Paeoniflorin)

Ready to launch a product featuring Paeonia lactiflora (Paeoniflorin)? Skip months of expensive wet-lab iterations. Generate a manufacturer-ready formulation in hours, instantly screened for physical incompatibilities and global regulatory compliance.

Build Science-Backed Formulation

Efficacy Evidence

Maximize Paeonia lactiflora (Paeoniflorin) Bioavailability

Need absolute proof that your Paeonia lactiflora (Paeoniflorin) extract actually absorbs? Stop blindly combining generic powders. Run a physics-based PBPK simulation to mathematically engineer peak clinical efficacy and targeted plasma concentrations.

Simulate Bioavailability

For R&D Labs & CDMOs

Paeonia lactiflora (Paeoniflorin) Degradation Testing

Is your Paeonia lactiflora (Paeoniflorin) payload degrading in the capsule before the expiration date? Stop waiting for costly bench testing. Run an accelerated digital twin to precisely model oxidation pathways and pH shifts before finalizing a manufacturing run.

Model Active Degradation