Home The Active Ingredient Matrix Paeonia lactiflora (Paeoniflorin)

Formulation Intelligence

Paeonia lactiflora (Paeoniflorin)

Accelerate your CDMO or DTC pipeline. Map the exact physiochemical constraints, bioavailability synergies, and optimal delivery mechanisms for Paeonia lactiflora (Paeoniflorin).

Paeonia lactiflora functions primarily as an immunomodulatory and anti-inflammatory agent by inhibiting the production of pro-inflammatory cytokines and modulating the NF-κB signaling pathway.

Verified Molecular Profiling (NIH PubChem)

PubChem CID

442534

Molecular Weight

480.5 g/mol

XLogP3 (Lipophilicity)

-1

IUPAC Name

[(1R,2S,3R,5R,6R,8S)-6-hydroxy-8-methyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9,10-dioxatetracyclo[4.3.1.02,5.03,8]decan-2-yl]methyl benzoate

Pharmacokinetic Synergies & Enhancers

Proven Synergy Pairings

  • Glycyrrhiza glabra for [Synergistic antispasmodic effects on smooth muscle]
  • Astragalus membranaceus for [Enhanced immunomodulatory response]

Biological Formulation Enhancers

  • Piperine for [Inhibition of glucuronidation to increase systemic bioavailability]
  • Quercetin for [Potential P-glycoprotein inhibition to enhance intestinal absorption]

Delivery System Constraints & Modeling

Every active compound behaves uniquely based on the physical matrix it is suspended in. Below are the known physical chemistry challenges for Paeonia lactiflora (Paeoniflorin) across standard consumer modalities.

💊 Standard Capsules

The hygroscopic nature of concentrated Paeonia extracts requires moisture-resistant excipients to prevent clumping and degradation within the capsule shell.

🍬 Gummy & Pectin Formats

High concentrations of paeoniflorin can impart a distinct bitterness and astringency that necessitates complex flavor masking and pH adjustment to maintain pectin stability.

🔬 Thin-Film Oral Strips

The high therapeutic dose required for efficacy often exceeds the 20-30mg payload capacity of standard thin-film polymer matrices.

For Brand Founders

Formulate with Paeonia lactiflora (Paeoniflorin)

Ready to launch a product featuring Paeonia lactiflora (Paeoniflorin)? Skip months of expensive wet-lab iterations. Generate a manufacturer-ready formulation in hours, instantly screened for physical incompatibilities and global regulatory compliance.

Build Science-Backed Formulation

Efficacy Evidence

Maximize Paeonia lactiflora (Paeoniflorin) Bioavailability

Need absolute proof that your Paeonia lactiflora (Paeoniflorin) extract actually absorbs? Stop blindly combining generic powders. Run a physics-based PBPK simulation to mathematically engineer peak clinical efficacy and targeted plasma concentrations.

Simulate Bioavailability

For R&D Labs & CDMOs

Paeonia lactiflora (Paeoniflorin) Degradation Testing

Is your Paeonia lactiflora (Paeoniflorin) payload degrading in the capsule before the expiration date? Stop waiting for costly bench testing. Run an accelerated digital twin to precisely model oxidation pathways and pH shifts before finalizing a manufacturing run.

Model Active Degradation