Pomegranate Seed Oil (Punicic Acid)

Accelerate your CDMO or DTC pipeline. Map the exact physiochemical constraints, bioavailability synergies, and optimal delivery mechanisms for Pomegranate Seed Oil (Punicic Acid).

Punicic acid is a conjugated linolenic acid isomer that functions as a potent dual PPAR-alpha and PPAR-gamma agonist, exerting significant anti-inflammatory and insulin-sensitizing effects through the modulation of eicosanoid synthesis and cytokine expression.

Verified Molecular Profiling (NIH PubChem)

PubChem CID

5281126

Molecular Weight

278.4 g/mol

XLogP3 (Lipophilicity)

6.4

IUPAC Name

(9Z,11E,13Z)-octadeca-9,11,13-trienoic acid

Pharmacokinetic Synergies & Enhancers

Proven Synergy Pairings

Conjugated Linoleic Acid (CLA) for synergistic lipid metabolism regulation
Curcumin for enhanced suppression of NF-κB mediated inflammatory pathways

Biological Formulation Enhancers

Mixed Tocopherols for preventing oxidative degradation of the polyunsaturated triene structure
Lecithin for improving intestinal micellar solubilization and lymphatic transport

Delivery System Constraints & Modeling

Every active compound behaves uniquely based on the physical matrix it is suspended in. Below are the known physical chemistry challenges for Pomegranate Seed Oil (Punicic Acid) across standard consumer modalities.

💊 Standard Capsules

The high degree of unsaturation in punicic acid necessitates nitrogen-flushed softgel encapsulation to prevent rapid oxidative rancidity and loss of pharmacological potency.

🍬 Gummy & Pectin Formats

Incorporating punicic acid into pectin-based gummies requires high-shear emulsification to prevent oil leaching and maintain structural integrity of the hydrocolloid matrix.

🔬 Thin-Film Oral Strips

The high therapeutic dose required for punicic acid exceeds the typical 50mg payload capacity of thin-film polymers, making it an inefficient delivery format for this lipid.

For Brand Founders

Formulate with Pomegranate Seed Oil (Punicic Acid)

Ready to launch a product featuring Pomegranate Seed Oil (Punicic Acid)? Skip months of expensive wet-lab iterations. Generate a manufacturer-ready formulation in hours, instantly screened for physical incompatibilities and global regulatory compliance.

Build Science-Backed Formulation

Efficacy Evidence

Maximize Pomegranate Seed Oil (Punicic Acid) Bioavailability

Need absolute proof that your Pomegranate Seed Oil (Punicic Acid) extract actually absorbs? Stop blindly combining generic powders. Run a physics-based PBPK simulation to mathematically engineer peak clinical efficacy and targeted plasma concentrations.

Simulate Bioavailability

For R&D Labs & CDMOs

Pomegranate Seed Oil (Punicic Acid) Degradation Testing

Is your Pomegranate Seed Oil (Punicic Acid) payload degrading in the capsule before the expiration date? Stop waiting for costly bench testing. Run an accelerated digital twin to precisely model oxidation pathways and pH shifts before finalizing a manufacturing run.

Model Active Degradation