Home The Active Ingredient Matrix Verbena officinalis (Verbenalin)

Formulation Intelligence

Verbena officinalis (Verbenalin)

Accelerate your CDMO or DTC pipeline. Map the exact physiochemical constraints, bioavailability synergies, and optimal delivery mechanisms for Verbena officinalis (Verbenalin).

Verbena officinalis functions primarily as a neuroprotective and galactagogue agent, exerting its effects through the modulation of GABAergic signaling and the inhibition of pro-inflammatory cytokines such as TNF-α and IL-6.

Verified Molecular Profiling (NIH PubChem)

PubChem CID

119594

Molecular Weight

166.99 g/mol

XLogP3 (Lipophilicity)

0.9

IUPAC Name

3-(dichloromethyl)-2H-furan-5-one

Pharmacokinetic Synergies & Enhancers

Proven Synergy Pairings

  • Valeriana officinalis for enhanced sedative and anxiolytic potentiation via synergistic GABA-A receptor modulation.
  • Vitex agnus-castus for optimized prolactin regulation and hormonal balance in lactogenic applications.

Biological Formulation Enhancers

  • Piperine for increased intestinal permeability and inhibition of P-glycoprotein-mediated efflux of iridoid glycosides.
  • Quercetin for potential inhibition of phase II metabolism, extending the half-life of circulating verbenalin.

Delivery System Constraints & Modeling

Every active compound behaves uniquely based on the physical matrix it is suspended in. Below are the known physical chemistry challenges for Verbena officinalis (Verbenalin) across standard consumer modalities.

💊 Standard Capsules

The hygroscopic nature of concentrated Verbena extracts necessitates the use of desiccants or moisture-resistant HPMC shells to prevent clumping and degradation of iridoid glycosides.

🍬 Gummy & Pectin Formats

High concentrations of verbenalin introduce significant bitterness and astringency that require complex masking agents and may interfere with pectin gelation kinetics.

🔬 Thin-Film Oral Strips

The high therapeutic dose required for effective neuroprotection exceeds the typical 20-30mg payload capacity of standard polymer thin-film matrices.

For Brand Founders

Formulate with Verbena officinalis (Verbenalin)

Ready to launch a product featuring Verbena officinalis (Verbenalin)? Skip months of expensive wet-lab iterations. Generate a manufacturer-ready formulation in hours, instantly screened for physical incompatibilities and global regulatory compliance.

Build Science-Backed Formulation

Efficacy Evidence

Maximize Verbena officinalis (Verbenalin) Bioavailability

Need absolute proof that your Verbena officinalis (Verbenalin) extract actually absorbs? Stop blindly combining generic powders. Run a physics-based PBPK simulation to mathematically engineer peak clinical efficacy and targeted plasma concentrations.

Simulate Bioavailability

For R&D Labs & CDMOs

Verbena officinalis (Verbenalin) Degradation Testing

Is your Verbena officinalis (Verbenalin) payload degrading in the capsule before the expiration date? Stop waiting for costly bench testing. Run an accelerated digital twin to precisely model oxidation pathways and pH shifts before finalizing a manufacturing run.

Model Active Degradation